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SR. SCIENTIST I, CHEMISTRY

Job Code C-0805

CovX is a division of Pfizer’s Biotherapeutic and Bioinnovation Center located in San Diego.  Since its founding, CovX has made advances toward building a portfolio of clinical candidates.  We use our proprietary technology to rapidly discover and develop long-acting biological therapeutics.  The CovX technology unites the therapeutic attractiveness of peptides with the beneficial properties of antibodies, resulting in a new biopharmaceutical called a CovX-Body.  The highly flexible nature of our technology enables us to identify high-value biological targets, efficiently create CovX-Bodies, and expeditiously move candidates to pre-clinical development and clinical evaluation.

As a member of the Chemistry team, this position requires a broad base of skills in the synthesis, purification and analysis of peptides and organic compounds.  Major responsibilities will include: 

  • Synthesize and characterize peptides, modified peptides and small molecules
  • Independently design and optimize drug candidates
  • Develop methods for analysis and characterization of peptides and small molecules
  • Contribute to the selection and prioritization of biologic targets and research programs
  • Develop preliminary analytical methods
  • Lead cross functional project teams
  • Generate reports to support ongoing research and development projects
  • Assist with the scale-up of peptides and drug candidates
  • Interface with other functions including development, biology, legal and CROs
  • Interface and communicate project progress with other Pfizer research sites
  • Assist in building chemistry organization
  • Hire and mentor scientific staff
  • Travel as required (foreign and domestic)
  • Other duties and special projects as required

Job Qualifications

  • PhD in organic or medicinal chemistry with 4-8 years experience or BS/MS with 10-20 years of relevant industrial experience
  • Extensive laboratory experience in the characterization and purification of peptides and organic compounds
  • Comprehensive knowledge of purification and separation techniques
  • Synthesis experience with structure or pharmacophore based drug design and familiarity with design of lead molecules and their modification required
  • Demonstrated problem-solving, communication and scientific track records
  • Solid written and oral communication skills, enthusiasm, integrity, self-motivation, strong interpersonal skills, and ability to act as a team player are necessary
  • Prior supervisory experience is desirable

CovX offers exciting careers for passionate, creative people who thrive on challenge and are motivated by the opportunity to have a big impact. We also provide competitive salaries and extensive benefits, including health, dental, vision, life insurance, and a 401(k) savings plan.  We are an equal opportunity employer M/F/D/V.  Interested candidates should send their resume to jobs@covx.com. Please ensure job code C-0805 is included in the subject line.


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