GROUP LEADER, CHEMISTRY

Job Code C-0804

CovX is a division of Pfizer’s Biotherapeutic and Bioinnovation Center located in San Diego.  Since its founding, CovX has made advances toward building a portfolio of clinical candidates.  We use our proprietary technology to rapidly discover and develop long-acting biological therapeutics.  The CovX technology unites the therapeutic attractiveness of peptides with the beneficial properties of antibodies, resulting in a new biopharmaceutical called a CovX-Body.  The highly flexible nature of our technology enables us to identify high-value biological targets, efficiently create CovX-Bodies, and expeditiously move candidates to pre-clinical development and clinical evaluation.

As a member of the Chemistry team, this position requires a broad base of skills in the synthesis, purification and analysis of peptides and organic compounds.  Major responsibilities will include: 

• Interface and communicate project progress with other Pfizer research sites
• Recommend biologic target and research program prioritizations
• Lead cross functional project teams
• Manage internal chemistry project efforts
• Independently design and optimize drug candidates
• Synthesize and characterize peptides, modified peptides and small molecules as needed
• Develop methods for analysis and characterization of peptides and small molecules
• Generate reports to support ongoing research and development projects
• Assist with the scale-up of peptides and drug candidates as needed
• Interface with other functions including development, biology, legal and CROs
• Assist in building chemistry organization
• Travel as required (foreign and domestic)
• Other duties and special projects as required

Job Qualifications

• PhD in organic or medicinal chemistry with 10-15 years experience or BS/MS with 15-20 years of relevant industrial experience
• Prior experience with structure or pharmacophore based drug designed and familiarity with design of lead molecules and their modification required
• Extensive laboratory experience in the characterization and purification of peptides and organic compounds
• Demonstrated problem-solving, communication and scientific track records
• Peptide drug design experience desirable
• Prior supervisory experience required
• Applicant should be able to conduct self-directed research and development, and provide technical leadership
• Solid written and oral communication skills, enthusiasm, integrity, self-motivation, strong interpersonal skills, and ability to act as a team player are necessary

CovX offers exciting careers for passionate, creative people who thrive on challenge and are motivated by the opportunity to have a big impact. We also provide competitive salaries and extensive benefits, including health, dental, vision, life insurance, and a 401(k) savings plan.  We are an equal opportunity employer M/F/D/V.  Interested candidates should send their resume to jobs@covx.com. Please ensure job code C-0804 is included in the subject line.

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